Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CR-48 | CR-48 | Cameroon | 2008 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V, T215F | K219Q | K103RS, Y181C, G190A | V108VI | V35T, E36ED, T69N, K101Q, S162AT, K173T, Q174K, D177E, I178M, T200A, Q207E, R211Q, L228R, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, S322T, I326V |
| >CR-48| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKSKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQTSMTKILEPFRTKNPEMVI CQYVDDLYVASDLEIGQHRAKIEELREHLLQWGFFTPDQKHQKEPPFRWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, N37I_D, I64L, H69K, K70E, L89M | M36K |
| >CR-48| codons 2-99 QITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEKILPGRWKPKMIGGIGGFIKVRQYDQ ILLEICGKEAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Charpentier, C | Virological failure and HIV type 1 drug resistance profiles among patients followed-up in private sector, Douala, Cameroon. | ARHR, 2011 |