Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, M184V, L210W, T215Y | K101E, V106VA | F227FL | K11R, K20R, E44ED, V118I, K122E, D123E, I135T, E138A, S162C, V179I, G196GAV, I202IV, Q207E, H208HY, R211K, A272P, I293V, P294S, E297R, E312T, Q334L |
| >CU1655-10| codons 1-335 PISPIETVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSATVLDVGDAYFSIPL DEEFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIVQHRTKVEELREYLWKWGFYTPDKKHQKEPPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVSLTREAE LELAENREILKTPVHGVYYDPSKDLIAEIQKQGLG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K20I, E35D, M36I, R57K, Q61E, L63P, I64L, A71V, I72T, V82I, I93L |
| >CU1655-10| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD EIPLEICGHKVTGTVLVGPTPINIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |