<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, M184V, L210W, T215Y   K101E, V106VA F227FL K11R, K20R, E44ED, V118I, K122E, D123E, I135T, E138A, S162C, V179I, G196GAV, I202IV, Q207E, H208HY, R211K, A272P, I293V, P294S, E297R, E312T, Q334L  
>CU1655-10| codons 1-335
PISPIETVPVRLKPGMDGPRVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSATVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII
YQYVDDLYVGSDLEIVQHRTKVEELREYLWKWGFYTPDKKHQKEPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVSLTREAE
LELAENREILKTPVHGVYYDPSKDLIAEIQKQGLG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   I13V, K20I, E35D, M36I, R57K, Q61E, L63P, I64L, A71V, I72T, V82I, I93L  
>CU1655-10| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
EIPLEICGHKVTGTVLVGPTPINIIGRNLMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012