<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V   L100I, K103KN P225H V35R, S48T, S68G, K173E, Q174K, V179I, R211S, W212G, A272P, V292I, I293IV, G335S K154N
>CU1650-09| codons 1-343
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICTELEKEGKITKIGPENPYNTPV
FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWNGSPAIFQSSMTKILEPFREKNPDIII
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLSGGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQSQWTYQIYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82F, L90M K43T L10I, M36V, R41K, I62V, L63P, I64V, I93L P9R
>CU1650-09| codons 3-99
ITLWQRRIVTIKIGGQLKEALLDTGADDTVLEEVNLPGKWTPKMIGGIGGFIKVRQYDQV
PVEICGHKAIGTVLVGPTPFNIIGRNLMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012