<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, K14T, G16E, K20I, E21Q, E35D, M36I, R41K, L63LV, I64IM, H69K, K70R, T74TA, L89M, T91A  
>CU1598-09| codons 1-98
PQITLWQRPLVAVTIEGQLIQALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVMEICGKRAIGAVLVGPTPVNIIGRNMLAQIGCTLN

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   V35T, E40D, S48ST, V60I, D123E, I142V, S162SG, Q174E, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, P294T, E297A, L325LW, I326V, Q334HY, G335D, Q340H Q91QL, Q182QL, Y342D
>CU1598-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVLLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQGSMTKILEPFRKENPDIVI
YLYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVTLTAEAE
LELAENREILKEPVHGVYYDPSKDWVAEIQKQGYDQWTYHIDQEPFKN

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012