<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184V A62AV, V75I, F116FY, Q151QL, K219E K101E, G190GA   E28EK, K32E, E36K, K122E, D123N, I135IT, S162SN, D177E, V179I, I202V, R211K, V245R, K249Q, A272P, K277KR, I293V, E297T, I329V N137NS
>CU963-10| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALVKICTEMEKEGKISKIGPENPYNTPV
FVIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYYSVPL
DENFRKYTAFTIPSTNSETPGIRYQYNVLPLGWKGSPAIFQNSMTKILEPFRKQNPEIII
YQYVDDLYVASDLEIGQHRTKVEELRQHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIRLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54IV   I13V, K20I, E35D, M36I, R41K, L63P, H69K, T74TS, V82VI, L89M  
>CU963-10| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKIVGGIGGFVKVRQYD
QIPIEICGKKAIGSVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012