Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU268-11 | CU268-11 | Cuba | 2011 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70G, T215Y | K219N | K103N, Y181C, G190A | A98G | K20R, K101R, V118I, K122P, I135T, S162C, R172K, D177G, H208HY, R211K, H221Y, V245Q, E248D, A272P, K277R, I293V, E297A, S322A |
| >CU268-11| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTGWRKLVDFRELNKRTQDFWEVQLGIPHPGGLRKNKSVTVLDVGDAYFSIPL DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFKKQNPGIVI CQYMDDLYVASDLEIGQHRTKIEELRQYLLKWGFYTPDNKYQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82T | L10I, I13V, K20IM, M36I, R41K, I66F, H69K, K70R, L89M | L76L* |
| >CU268-11| codons 1-99 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD QILIEFCGKRAIGTV*VGPTPTNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |