<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T   L10I, I13V, K20IM, M36I, R41K, I66F, H69K, K70R, L89M L76L*
>CU268-11| codons 1-99
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD
QILIEFCGKRAIGTV*VGPTPTNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70G, T215Y K219N K103N, Y181C, G190A A98G K20R, K101R, V118I, K122P, I135T, S162C, R172K, D177G, H208HY, R211K, H221Y, V245Q, E248D, A272P, K277R, I293V, E297A, S322A  
>CU268-11| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTGWRKLVDFRELNKRTQDFWEVQLGIPHPGGLRKNKSVTVLDVGDAYFSIPL
DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFKKQNPGIVI
CQYMDDLYVASDLEIGQHRTKIEELRQYLLKWGFYTPDNKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTAEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQ

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012