<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54M, V82A, L90M K43T Q2H, L10V, K14R, L19I, K20R, E35D, M36I, R41K, L63P, H69K, K70KR, A71V, L89I, T91S, I93L  
>CU2035-09| codons 1-99
PHITLWQRPVVTIRIGGQIREALLDTGADDTVLEDINLPGKWTPKIIGGIGGFMKVRQYD
QIPIEICGKRVIGTVLVGPTPANIIGRNIMSQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, M184V L74S, T215S, K219Q Y188L   V35T, E36A, T39E, V60I, F87L, W88R, D121Y, K122E, D123N, I135V, K173A, Q174R, D177E, V179I, T200A, K201KI, E203D, Q207E, R211K, F214L, V241VA, V245P, A272P, E291D, V292I, I293IV, H315HQ F130S, N136D, Y146C, K154S
>CU2035-09| codons 2-329
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPIF
AIKKKNSDRWRKSVDFRELNKRTQDLREVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLY
ENFRKYTASTIPSVDNETPGIRYQCNVLPQGWSGSPAIFQSSMTKILEPFRARNPEIIIY
QYVDDLLVGSDLEIGQHRAIIDELREHLLKWGLSTPDQKHQKEPPFLWMGYELHPDKWTA
QPIPLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAEL
ELAENREILKEPVQGVYYDPSKDLIAEI

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012