<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215F   Y181I   I31L, T69N, A98S, K122E, I135L, S162C, D177E, I178L, V179I, T200A, R211K, L228Q, V245E, D250E, A272S, K277R, T286A, I293V, E297T, I329V, Q334E  
>CU182-11| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPELII
IQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFFTPDKKHQKEPPFQWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTEVVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGEG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90LM   I13V, I15S, G16R, K20I, E35D, M36I, R41K, H69K, T74TS, V82I, L89M  
>CU182-11| codons 1-99
PQITLWQRPLVTVKSRGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGSVLVGPTPINIIGRNMMTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012