<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215TI, K219Q     E28A, K49R, T69TN, A98S, V118VI, D123E, I135T, E169D, I178L, V179VI, G196E, T200TA, E204K, Q207E, F214L, V245M, A288S, I329L  
>CU121-11| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALVEICTEMEKEGKISRIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDLII
YQYVDDLYVGSDLEIEQHRAKIEKLREHLLRWGLITPDQKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82A, L90M L89LV L10I, I13V, Q18H, K20M, E35D, M36MI, R41K, K45R, L63P, A71V, I93L, C95F  
>CU121-11| codons 1-99
PQITLWQRPIVTVKIGGHLMEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNVMTQLGFTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012