<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, I84V L24I, L33F L10I, T12S, G16A, L19I, K20V, E35D, M36I, N37S, R41K, L63P, H69K, A71AV, T74S, L89M, I93L  
>CU2007-09| codons 1-99
PQITLWQRPIVSIKIAGQIVEALIDTGADDTVFEDISLPGKWKPKIIGGIGGFVKVRQYD
QIPIEICGKKVIGSVLVGPTPANVIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V V75VI, K219Q Y181C   T27S, V35T, T39D, S48T, K49R, E53D, V60I, V90VI, K122E, D123N, I135L, K166R, E169A, K173A, G196R, T200A, I202V, Q207E, R211K, H221Y, L228H, V245Q, A272P, K277R, E291ED, V292I, I293V, D324E, Q334H, G335D  
>CU2007-09| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICDEMEKEGKITRIGPDNPYNTPI
FAIKKKNSTRWRKLIDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILAPFRAQNPDIVI
CQYVDDLYVGSDLEIRQHRAKVEELREHLLKWGFTTPDQKYQKEPPFHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGHDQWTYQ

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012