Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU599-10 | CU599-10 | Cuba | 2010 | HIV1 | CRF18_cpx | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I50V | L10V, I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V82I, L89M |
| >CU599-10| codons 1-99 PQITLWQRPVVTVKIEGQLIEALLDTGADDTVLEDINLPGKWKPKLIGGVGGFIKVRQYD QILIEICGKRAIGSVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69S_RG, K70R, M184V, T215F | D67S, F77FL, K219E | K101E, Y181C, G190A | A98G, V108I | E28K, K32E, V35T, V60I, S68G, V106I, L109V, V118I, K122P, D123E, I135V, D177E, Q207E, R211K, F214L, D218E, L228H, V245Q, A272P, V276T, K277R, L283I, T286A, A288T, V292I, I293V, E297A | I159L, I180IM |
| >CU599-10| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICTELEKEGKISKIGPENPYNTPI FAIKKKSGSRWRKLVDLRELNKRTQDFWEVQLGIPHPGGLEKKKSITIVDVGDAYFSIPL DPEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPALFQSSMTKILEPFRKQNPEIVM CQYVDDLYVASDLEIGQHRTKIEELREHLLKWGLFTPEEKHQKEPPFHWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKTRQLCKLIRGAKTLTEIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |