<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I50V   L10V, I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V82I, L89M  
>CU599-10| codons 1-99
PQITLWQRPVVTVKIEGQLIEALLDTGADDTVLEDINLPGKWKPKLIGGVGGFIKVRQYD
QILIEICGKRAIGSVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69S_RG, K70R, M184V, T215F D67S, F77FL, K219E K101E, Y181C, G190A A98G, V108I E28K, K32E, V35T, V60I, S68G, V106I, L109V, V118I, K122P, D123E, I135V, D177E, Q207E, R211K, F214L, D218E, L228H, V245Q, A272P, V276T, K277R, L283I, T286A, A288T, V292I, I293V, E297A I159L, I180IM
>CU599-10| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKSGSRWRKLVDLRELNKRTQDFWEVQLGIPHPGGLEKKKSITIVDVGDAYFSIPL
DPEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPALFQSSMTKILEPFRKQNPEIVM
CQYVDDLYVASDLEIGQHRTKIEELREHLLKWGLFTPEEKHQKEPPFHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKTRQLCKLIRGAKTLTEIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012