<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, Y115F, M184V, L210W, T215Y       V35I, T39A, V118I, K122E, D123N, S134G, T139TR, K173S, Q174K, D177E, V179I, T200A, Q207DN, R211K, V245K, D250E, A272P, I293V, P294T, S322A, A327T, G335D D110N, R172R*
>CU1908-09| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLNVGDAFFSIPL
DENFRKYTAFTIPGINNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPF*SKNPEIII
YQYVDDLYVGSDLEIGQHRAKIEELRNHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVTLTEEAE
LELAENREILKEPVHGVYYDPAKDLITEIQKQGQDQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82F, L90M L33F, T74P K20I, E35N, M36I, R41K, K43R, F53Y, R57K, I62V, L63P, H69K, I85V, L89M R87RK
>CU1908-09| codons 14-99
KIGGQLIEALLDTGADDTVFENINLPGKWRPKIIGGIGGYVKVKQYDQVPIEICGKKAIG
PVLVGPTPFNIVGKNMMTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012