<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, L210W T215C, K219E Y181C A98G K122P, I135L, S162C, D177E, V179IS, I202V, R211K, L228H, V245Q, E248D, A272P, K277R, I293V, E297T  
>CU1288-10| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEISI
CQYVDDLYVGSDLEIGQHRTKVEELRQHLWKWGFCTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54L, I84V V11I, L33F, Q58E L10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89M  
>CU1288-10| codons 1-99
PQITLWQRPIITVRVEGQPVEALLDTGADDTVFENIDLPGRWKPKIIGGIGGFLRVKEYD
HISIEICGKRAMGTVLVGPTPVNVVGRNMLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012