<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, E21EK, E35D, M36I, N37D, R41K, K43R, Q61EG, L63P, H69Q Q7L, G52GS
>CU646-09| codons 1-99
PQITLWLRPLVTIKIGGQLRKALLDTGADDTVLEDIDLPGKWRPKMIGGIGSFIKVRQYD
GIPIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, M184V, L210W, T215Y   Y181C, G190A V108VI V35T, E44D, K49R, V111VI, V118VI, K122E, I142V, E169D, F171FL, D177E, Q207E, V245K, A272P, K277R, T286A, I293V, K311KN, P313Q, I329V, G335D F61Y, K281KI
>CU646-09| codons 1-347
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISRIGPENPYNTPV
YAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDIGDAYFSIPL
DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPLRKQNPEIVI
CQYVDDLYVASDLEIGQHRTKIEELREHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCILLRGAKALTEVVPLTEEAE
LELAENREILNEQVHGVYYDPSKDLIAEVQKQGQDQWTYQIYQEPFK

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012