<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70KR, L74I, M184V, T215F K219Q Y181C V108I V35T, E36EA, T39D, K46KQ, D121H, K122E, K173T, D177E, T200A, Q207G, R211Q, D218E, V245Q, A272P, E291D, V292I, E298ED, E312Q, P313PS, I326V  
>CU2104-09| codons 1-329
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGQISKIGPENPYNTPV
FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELRGHLLQWGFFTPEQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIIPLTEDAE
LELAENREILKQSVHGVYYDPSKDLVAEI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48GV, I54MV, I84V, L90LM L33F, Q58QE, T74PS, N83ND L10I, E34K, E35D, M36I, N37S, R41K, L63LP, G68GE, H69K, A71AV, L89IM, I93L  
>CU2104-09| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVFKDISLPGKWKPKMIVGIGGFVKVREYD
QIPIEICEKKVIGSVLVGPTPVDVIGRNMMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012