Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU2069-10 | CU2069-10 | Cuba | 2010 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | G190A | A98G | K49R, K104KR, D123E, I135L, I142T, S162SN, E169D, F171FY, D177E, I178L, T200A, K201KR, E204K, Q207E, F214L, V245MT, A272P, K277R, R307K, I326V, I329L |
| >CU2069-10| codons 1-340 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKRSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSLNNETPGTRYQYNVLPQGWKGSPAIFQNSMTKILDPYRKQNPELVI YQYVDDLYVASDLEIGQHRARIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE LELAENKEILKEPVHGVYYDPSKDLVAELQKQGQGQWTYQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| P1L, T12P, I13V, G16E, N37C, P39S, I62V, L63H, I64V, V77I | R8G |
| >CU2069-10| codons 1-99 LQITLWQGPLVPVKIEGQLKEALLDTGADDTVLEEMCLSGRWKPKMIGGIGGFIKVRQYD QVHVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |