<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A   L10V, T12I, I13V, K20I, E35D, M36I, N37DE, R41K, H69K, T74S, L89I  
>CU376-10| codons 1-99
PQITLWQRPVVIVKIGGQLIEALLDTGADDTVLEDIELPGKWKPKMIVGIGGFVKVRQYD
QILIEICGKKAIGSVLVGPTPANIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E Y181C V108I V35T, T39K, E40D, T69N, K122E, D123S, I135IT, K173S, Q174K, V179I, G196E, T200A, R206K, Q207A, R211S, L228H, V245Q, E248N, K281KR, T286A, E291D, V292I, I293V, P294T, Q334H, G335D  
>CU376-10| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKDMEKEGKISKIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPDIII
CQYVDDLYVGSDLEIEQHRAKIEELKAHLLSWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQ

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012