Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU1288-09 | CU1288-09 | Cuba | 2009 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46L, L76V, V82A | L33LF, L89V | L10I, I13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92K |
| >CU1288-09| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADDTIFEEIDLPGKWRPKLIGGIGGFIKVRQYD NIPIEICGHKVIGTVVVGPTPANIIGRNVLTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | L100I, K103N | V35E, T39A, K43N, E44D, K49R, V60I, V111VI, V118I, K122E, T139R, E169R, K173E, D177E, T200A, E203Q, Q207D, V245T, D250E, A272S, L283I, A288P, I293V, E297A, P313S, V317A, I329V, Q332L, G335D | G152GV, I274IM |
| >CU1288-09| codons 1-340 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAELENDGKISRIGPENPYNTPI FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDIGDAYFSIPL DEDFRKYTAFTIPSINNERPGIRYQYNVLPQVWKGSPAIFQSSMTKILRPFREQNPEIVI YQYVDDLYVGSDLEIGQHRAKIQELRDHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYSGMKVKQLCKLIRGTKPLTEVVPLTAEAE LELAENREILKESVHGAYYDPSKDLIAEVQKLGQDQWTYQ |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |