<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T, I84V, L90M L33I, L89V L10I, I13A, K20I, M36I, R41K, L63LP, C67E, H69K, A71V  
>CU2143-09| codons 1-99
PQITLWQRPIVTAKIGGQLIEALLDTGADDTVIEEINLPGKWKPKIIGGIGGFIKVRQYD
QIPIEIEGKKVIGTVLVGPTPTNVIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, T215Y   K103N, G190GA V179VE, K238T V35T, T39A, V60I, A98S, D121Y, K122E, I135V, I142V, K173I, Q174K, D177E, I178LM, G196K, T200A, Q207E, L228R, V245Q, E248EDKN, A272P, K277R, E291D, V292I, I293V, P294T, E297A, D324E, I326IT, I329V  
>CU2143-09| codons 1-329
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMEI
YQYVDDLYVASDLEIKQHRAKIEELREHLLRWGFYTPDKKHQKEPPFRWMGYELHPDTWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTAEAE
LELAENREILKEPVHGVYYDPSKELTAEV

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012