<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, K70R, L210W, T215Y K219E K101E, Y181C, G190A A98G E28K, K32E, V35IT, E36A, T39D, E44D, V60I, K66E, V118I, K122E, S162C, K173T, D177E, V179I, T200A, E203K, Q207E, H208HY, R211Q, D218E, L228R, V245Q, A272P, K277R, E291D, V292I, E298ED, Q334D, G335D  
>CU728-10| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICDELEKDGKISKIGPENPYNTPI
FAIKKEDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTQNPEIII
CQYMDDLYVASDLEIGQHRAKIKELREYLWQWGFYTPEEKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEDAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, L90M L33F W6G, L10V, N37S, R41K, K55R, Q61E, L63P, H69K, T74S, V77I, V82VI, I85V, L89M, I93L  
>CU728-10| codons 1-99
PQITLGQRPVVTIKIGGQLKEALLDTGADDTVFEEMSLPGKWKPKIIGGVGGFIRVRQYD
EIPIEICGKKAIGSVLIGPTPINIVGRNMMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012