<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, T215Y   K101E, Y181C, G190GE   V35M, T39K, K43E, D123E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272S, T286A, E291D, V292I, I293V, E297A, V317A, I326V  
>CU544-09| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICKELEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
CQYVDDLYVESDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGAYYDPSKDLVAEIQKQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, I84V, L90M L10F, V11VI, L33I, Q58E, G73S, T74P, N88G, L89V I13AV, K14R, K20IT, E35N, M36I, N37D, R41K, I62V, L63V, H69K, K70R  
>CU544-09| codons 1-99
PQITLWQRPFITVRIGGQLTEALLDTGADDTVIENIDLPGKWKPKIVGGIGGFVKVREYD
QVVIEICGKRAISPVLVGPTPVNVIGRGVMTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012