<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54L, V82A, L90M L33F, K43T, G73T L10I, I15V, L19LI, K20R, E35D, M36I, N37D, R57K, I62V, L63P, A71V, I72L, I85V  
>CU1022-09| codons 1-99
PQITLWQRPIVTIKVGGQIREALLDTGADDTVFEDIDLPGRWTPKLIGGIGGFLKVKQYD
QVPIEICGHKVLTTVLVGPTPANIVGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, L210W, T215Y V75M, K219E K103N   V35M, T39TA, E40F, K43E, I94L, V118I, K122E, D123E, S162A, Q174K, D177N, I178M, T200E, Q207E, L228H, P243S, A272P, K275R, K277R, R284RK, I293V, E297H, E312T, Q334L, F346N E203N
>CU1022-09| codons 1-347
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAFMEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGLPHPAGLKKNKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKKNPNMVI
YQYVDDLYVGSDLEIGQHREKINELREHLWRWGFYTPDEKHQKEPPFHWMGYELHPDKWT
VQSIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLKGTKALTEVVPLTHEAE
LELAENREILKTPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPNK

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012