<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54AV, V82A L33F, T74AP, N83ND L10I, I13V, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, L89M  
>CU772-10| codons 1-99
PQITLWQRPIVTVKVEGQLREALLDTGADDTVFEDIDLPGKWKPKLIGGIGGFVKVKQYD
QITIDICGHKAIGPVLVGPTPADIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V V75I, F116Y Y181C   V35T, V60I, S68G, K104R, D123E, I132L, S162C, K173I, Q174K, Q207E, R211K, F214L, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297A, Q334H, G335D  
>CU772-10| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKRKDGTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYYSVPL
DKEFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRIKNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKN

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012