<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LV, M184V, L210W, T215Y D67DE K103N K238T V35T, E36K, T39A, K43KE, K49R, V60I, S68G, V118I, D121Y, K122E, S162DN, E169D, Q174R, D177E, I178M, T200A, E203EK, Q207E, H208HY, R211RK, K223KQ, V245T, E248D, A272P, T286A, P294A, E297EK, P313Q, I329V, G333E, G335GE  
>CU461-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTKICAELEEEGKISRIGPENPYNTPI
FAIKKKEGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILDPFRKRNPEMVI
YQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTPDKKHQQEPPFLWMGYELHPDTWT
VQPITLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIALTKEAE
LELAENREILKEQVHGVYYDPSKDLIAEVQKQEQEQWTYQIYQEPFKN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M G73S L10I, K20R, E35D, M36I, R41K, I62V, L63P, H69Q, A71V, I93L  
>CU461-09| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
QVPIEICGQKVISTVLVGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012