<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, I54M, L90M L33F, N88D T12S, I13V, K14R, I15V, E35D, M36I, N37S, R41K, L63P, H69K, T74S, L89I, I93L  
>CU1452-09| codons 1-99
PQITLWQRPLVSVRVGGQLKEALLDTGADNTVFEDISLPGKWKPKMIGGIGGFMKVRQYD
QIPIEICGKKAIGSVLVGPTPVNIIGRDIMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R T215I, K219Q     V35T, E36A, T39D, K49R, V60I, K122E, I135T, K173T, Q174K, D177E, T200A, Q207G, R211Q, V245Q, A272P, K277R, K281R, E291D, V292I, I326V, Q334D, G335D  
>CU1452-09| codons 1-347
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISRIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLQWGFITPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGDDQWTYQIYQEPFK

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012