Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V, L90M | L33I, K43KT | L10V, L19I, K20R, E35D, M36I, L63P, A71V | G40E |
| >CU2140-09| codons 1-99 PQITLWQRPVVTIKIGGQIREALLDTGADDTVIEDINLPERWTPKIIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPTNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215Y | K219Q | G190A | A98G, V108I | K49R, V106I, K122E, D123E, E169D, I178F, T200A, E203K, Q207E, H208Y, K223E, L228HP, V245MR, A272P, K275R, I329L, Q334E |
| >CU2140-09| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSITILDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDFVI YQYVDDLYVASDLEIGQHRAKIKELREYLLRWGFYTPDQKHQEEPPFPWMGYELHPDKWT VQPIRLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGEG |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |