<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W   K103N   E28K, K32E, V35T, E36ED, K43N, V60I, V118I, D121H, K122E, E169D, Q174R, D177E, T200A, I202V, Q207E, R211K, V245T, S251T, A272P, T286A, E297A, K311R, I329V, G335D K154K*, W229WG
>CU1805-09| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTDICTELENEGKISKIGPENPYNTPI
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGW*GSPAIFQSSMTKILDPFRKRNPEIVI
YQYVDDLYVGSDLEIGQHRAKVEELREHLWKWGFTTPDKKHQKEPPFLGMGYELHPDKWT
VQPITLPEKDTWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTAEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGQDQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M   L10I, K20I, M36I, N37D, R41K, K43KR, Q61N, L63P, I64L, H69Q, A71V, I72IV, I93L  
>CU1805-09| codons 1-99
PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEIDLPGKWRPKIIGGIGGFVKVRQYD
NIPLEICGQKVVGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012