<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A F53L L10I, I13V, G16E, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61H, L63T, E65D, I72T, T74A, L89M  
>CU2073-09| codons 1-99
PQITLWQRPIVTVKIEGQLREALLDTGADDTVLEDIELPGKWKPKLIGGIGGLVRVKQYD
HITIDICGHKATGAVLVGPTPANIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y K219R V106A F227L V35I, T39A, E44D, V118I, D123E, S162C, K173A, Q174K, I178L, V179I, T200A, E203D, Q207E, H208Y, R211K, K223Q, V245Q, E248D, D250E, A272P, T286A, A288T, E291D, V292I, I293V, E297T L205I
>CU2073-09| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPDLII
YQYVDDLYVGSDLEIGQHRAKIDEIREYLWKWGFYTPDRKHQQEPPLLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012