<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V, L90M   E35D, M36I, R41K, L63P, H69K, L89M, I93L  
>CU1316-09| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNVIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210LW, T215Y   K101E, Y181C, G190A   V35T, E36A, T39D, K64N, F87L, S117P, K122E, D123G, I142V, K173IT, D177E, T200A, Q207R, R211K, V245Q, A272P, K277R, E291D, V292I, I329IV, Q334D, G335D N57K, R72S, P97H, F116S
>CU1316-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDELEKEGKISKIGPENPYKTPV
FAINKKDSTKWSKVVDFRELNKRTQDLWEVQLGIPHHAGLEKKKSVTVLDVGDAYSPVPL
DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI
CQYVDDLYVASDLEIGQHRAKIEELRRHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGDDQWTYQIYQEPFKN

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012