<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54M, V82A, L90M L33F T4H, L5S, L10I, N37ND, R41RK, K55R, R57K, L63P, A71V, V77I, I93L, C95F  
>CU582-09| codons 1-99
PQIHSWQRPIVTIKIGGQLKEALLDTGADDTVFEEMDLPGKWKPKLIGGIGGFMRVKQYD
QIPIEICGHKVIGTVLIGPTPANIIGRNLMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, Q151M, M184V, T215F K219Q     K20R, K49R, V60I, V118I, K122E, D123E, I135T, E169D, Q174R, D177E, I178L, V179I, Q207E, H208HY, R211K, F214L, V245M, A272P, A288T, I293V, I329L, G335D E29ED, G99GR, G155R
>CU582-09| codons 1-348
PISPIETVPVKLKPGMDGPRVKQWPLTEDKIKALVEICTEMEKEGKISRIGPENPYNTPI
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPARLKKKKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKRSPAIFQSSMTKILDPFRKRNPELII
YQYVDDLYVGSDLEIGQHRTKIEELREYLLKWGLFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKTLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQDQWTYQIYQEPFKN

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012