<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W, T215Y V75T, K219N K101E, Y181C, G190A   V35T, V111I, D121Y, K122E, I135T, S162Y, D177E, I178L, V179VI, T200A, E204A, Q207E, R211K, V245T, D250E, A272S, K277R, T286A, E297K, P313S, V317A, I329V, G335D N137H
>CU749-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDIGDAYFSVPL
YEDFRKYTAFTIPSTNHETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPELII
CQYVDDLYVASDLEIGQHRAKIEALREHLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTEVIPLTKEAE
LELAENREILKESVHGAYYDPSKDLIAEVQKQGQDQWTYQIYQEPFKN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I84V N83D L10I, I15V, G16E, K20R, M36I, R41K, D60E, I62IV, L63T, V82I, L89LF  
>CU749-09| codons 1-99
PQITLWQRPIVTIKVEGQLREALLDTGADDTVLEEINLPGKWKPKLIGGIGGFIKVRQYE
QVTIEICGHKAIGTVLVGPTPIDVIGRNFLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012