<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y   K101E, Y181C, G190S   E28EG, V35M, K43N, E44D, V106I, V111I, V118I, K122E, D123N, I135T, Q174R, D177E, I178M, V189I, T200A, I202V, Q207D, H208Y, V245T, D250E, A272S, T286A, I293V, E297K, P313T, V317A, I329V, Q334D N136ND
>CU25-10| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTGEKIKALMEICTELENDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSITVLDIGDAYFSIPL
DENFRKYTAFTIPSTDNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEMVI
CQYVDDLYISSDLEIGQHRAKVEELRDYLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPLTKEAE
LELAENREILKETVHGAYYDPSKDLIAEVQKQGDG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L33F, K43T, F53L, G73S L10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93L  
>CU25-10| codons 1-99
PQITLWQRPVVTVKIGGQIREALLDTGADDTVFEDIDLPGKWTPKLIGGIGGLVRVRQYD
QIPIEICGKTIISTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012