<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M F53L, L89V I13V, K14R, K20I, E35D, M36I, N37D, R41K, K45R, L63P, C67CY, H69K, A71I  
>CU1315-09| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPRMIGGIGGLVKVRQYD
QIPIEIYGKKIIGTVLVGPTPVNIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, L210W, T215F   M230L F227L I2V, V21I, V35T, V60I, T107S, L109I, V118I, K122P, I135T, Q174A, D177G, G196E, T200A, Q207E, R211K, L228R, V245Q, A272S, V276I, L283I, T286A, E291D, V292I, I293V, E297A, I326V, Q334H, G335D  
>CU1315-09| codons 1-344
PVSPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVIDVGDAYFSIPL
DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKANPGIVI
YQYVDDLYVGSDLEIEQHRAKIEELREHLWKWGFFTPDKKHQKEPPLRWLGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKIKQLCKLIRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGHDQWTYQIYQE

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012