Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU1315-09 | CU1315-09 | Cuba | 2009 | HIV1 | CRF18_cpx | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | F53L, L89V | I13V, K14R, K20I, E35D, M36I, N37D, R41K, K45R, L63P, C67CY, H69K, A71I |
| >CU1315-09| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPRMIGGIGGLVKVRQYD QIPIEIYGKKIIGTVLVGPTPVNIIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, M184V, L210W, T215F | M230L | F227L | I2V, V21I, V35T, V60I, T107S, L109I, V118I, K122P, I135T, Q174A, D177G, G196E, T200A, Q207E, R211K, L228R, V245Q, A272S, V276I, L283I, T286A, E291D, V292I, I293V, E297A, I326V, Q334H, G335D |
| >CU1315-09| codons 1-344 PVSPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVIDVGDAYFSIPL DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKANPGIVI YQYVDDLYVGSDLEIEQHRAKIEELREHLWKWGFFTPDKKHQKEPPLRWLGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKIKQLCKLIRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGHDQWTYQIYQE |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |