<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215F K70S, K219Q Y181C   K32Q, V35K, T39A, K49R, V60I, V90I, V111I, V118I, K122E, D123N, I135R, Q197K, T200A, I202V, E203K, Q207D, H208Y, R211K, D218E, L228H, V245T, D250E, A272S, T286A, I293V, E297K, L301I, P313Q, I329V F160Y
>CU691-09| codons 1-331
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIQALKEICAELEKEGKISRIGPENPYNTPI
FAIKKKNSTSWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDIGDAYFSIPL
DENFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIYQSSMTKILEPFRKQNPDIVI
CQYVDDLYVGSDLEIGKHRAKVKELRDYLWKWGFFTPEQKHQKEPPFHWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPLTKEAE
IELAENREILKEQVHGVYYDPSKDLIAEVQK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, V32I, M46I, I47V, I54L, V82A L10LF, L33F, F53FL, Q58E, N88D I13V, I15V, L19I, K20R, E35D, M36L, N37T, R41T, K45R, D60E, L63P, H69Q, K70R, I72V, V77I, L89F  
>CU691-09| codons 1-99
PQITLWQRPFVTVKVGGQIREALLDTGADNTIFEDLTLPGTWKPRIVGGIGGLLKVREYE
QIPIEICGQRAVGTVLIGPTPANIIGRDFLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012