<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y   Y181C A98G, V108VI P9PS, V35T, E44D, V60I, K64R, V118I, K122E, I135V, K173I, Q174K, D177E, I178IM, I195L, T200A, E203K, H208Y, R211D, K223E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E297A, D324E, I329V G273GE
>CU1342-10| codons 1-334
PISPIETVSVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPI
FAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI
CQYVDDLYVGSDLELGQHRAKIKELRQYLWDWGFYTPDKKHQEEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPEIKVKQLCKLLRGAKALTDIVTLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63P, H69K, V82I, L89M  
>CU1342-10| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012