Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, M36ML, N37S, P39PS, I62V, L63H, I64V |
| >CU1462-10| codons 1-99 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEELSLSGRWKPKMIGGIGGFIKVRQYD QVHVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181YC | P4PH, E44ED, K49R, D123E, I135IT, T165TILP, E169D, D177E, I178L, Q207E, R211RK, F214L, L228LR, V245M, A272P, K311R, I329L, G335S |
| >CU1462-10| codons 1-340 PISHIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKDGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMPKILDPFRKQNPELVI CQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFRWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILREPVHGVYYDPSKDLIAELQKQGQSQWTYQ |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |