<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V L33I, G73S I13V, K14R, K20I, E35D, M36I, H69K, A71V, T74S, V75I, L89T  
>CU2041-09| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVIEDINLPGRWKPKIIGGIGGFVKVRQYD
QILIEICGKKVISSILVGPTPVNIIGRNTLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LI, M184V, L210W, T215Y       V21I, V35T, V60I, K122P, I135L, Q174E, D177E, T200A, E204D, Q207A, R211K, L228R, V245Q, A272S, V276I, L283I, T286A, E291D, V292I, I293V, E297A, I326IV K43LM
>CU2041-09| codons 1-330
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTELEMEGKISKIGPENPYNTPI
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKENPEIVI
YQYVDDLYVGSDLEIGQHRAKIEDLRAHLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKIKQLCKLIRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQ

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012