<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y V75M     K43Q, E44D, A98S, V118I, K122E, I135V, S162C, D177E, T200A, R211K, L228K, D250E, A272S, A288S, I293V, E297A  
>CU1023-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV
FAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQKEPPFKWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V L89V L10I, I13A, K14R, K20IV, M36I, N37D, R41K, K55R, R57RG, I66F, H69K, T74S G73E, T80V
>CU1023-09| codons 1-99
PQITLWQRPIVTARIGGQLVEALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVRVGQYD
QILIEFCGKKAIESVLVGPVPTNVIGRNVLTQIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012