<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82C, L90M   L10I, E34K, R41K, I62V, L63H, H69Y, A71V, I72V, V77I, I93L  
>CU1383-10| codons 8-99
RPIVTIKIGGQLKEALLDTGADDTVLKEMNLPGKWKPKMIVGIGGFVKVRQYDQVHIEIC
GYKVVGTVLIGPTPCNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69S_SS, L74V, M184V, L210W, T215Y   Y181I   K122E, I142T, T165L, D177E, V179I, G196E, I202V, Q207E, R211K, L228H, K277R, T286A, A288S, P294T, E297R, K311R, Q334L  
>CU1383-10| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSSKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMLKILEPFRKQNPEIII
IQYVDDLYVGSDLEIEQHRTKVEELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKSLTEVITLTREAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGLG

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012