Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU294-10 | CU294-10 | Cuba | 2010 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI+PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V | Q58E, L89V | I13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IV |
| >CU294-10| codons 1-99 PQITLWQRPLVTAKIGGQPIEVLLDTGADDTVVEDIDLPGRWKPKLIGGIGGFVKVREYD QVPIEFCGKKVIGAVLVGPTPVNVIGRNVLTKVGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, K70R, L74I | L100I, K103N | V35I, T39TA, V60I, W88G, S117T, D121N, K122E, D123S, F124L, I135V, Y144F, A272P, K281R, V292I, I293V, E297Q | A98P, A114P, T128S, N147M |
| >CU294-10| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPI FAIKKKDSDRWRKIVDFRELNKRTQDFGEVQLGIPHPPGIKKNKSVTVLDVGDPYFTVPL NESLRKYSAFTIPSVNNETPGIRFQYMVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEIVPLTQEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Kouri, V | High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. | J Clin Virol, 2012 |