<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, Q151M, M184V, T215F F116Y K101E, Y188L   E28K, K32E, V35T, T39AS, K49R, V60I, V111I, K122E, E169D, P170L, K173Q, D177G, G196E, Q197K, Q207E, H208F, R211K, I244V, V245T, D250E, A272S, A288S, E297K, P313Q, I329V, Q334N, G335D  
>CU373-10| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICSELEKEGKISRIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDIGDAYYSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILDLFRQQNPGIVI
YQYVDDLLVGSDLEIEKHRTKIEELREFLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPVTLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKSLTEVIPLTKEAE
LELAENREILKEQVHGVYYDPSKDLIAEVQKQGNDQWTYQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L24I, L33F L10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93L  
>CU373-10| codons 1-99
PQITLWQRPIVTVKIGGQLREALIDTGADDTVFEDIDLPGKWKPKIIGGIGGFVKVRQYE
QVPIEICGHKVIGTVVVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012