<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13IV, I15V, G16GE, Q18R, K20KR, E35D, M36MI, N37NS, R41K, I62IV, L63LP, H69K, K70KR, T74TS, V77VI, L89M, I93IL Q7P
>CU300-10| codons 1-99
PQITLWPRPLVTVKVEGRLREALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD
QVPIEICGKRAIGSVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215TS, K219Q K103N, Y181YC   K32I, V35T, E36EA, T39D, K64KR, V118VI, K122E, D123DG, I135IR, S162N, K173I, D177DE, I178IM, V179VI, T200A, Q207DE, H208HY, F214FL, D218DE, H221HY, L228LH, V245Q, E248D, A272PS, K281KR, E291D, V292VI, I293V, K311KR, E312EDKN, D324DE, Q334DH, G335D  
>CU300-10| codons 1-340
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIIALTAICDEMEKEGKISKIGPENPYNTPV
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DEGFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRIQNPEMII
CQYMDDLYVGSDLEIGQHRAKIEELREYLLRWGLSTPEQKYQKEPPFHWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGTKALTDIVPLTEEAE
LELAENREILRNPVHGVYYDPSKELIAEIQKQGHDQWTYQ

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012