<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI+PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184V, L210W, T215Y   L100I, K103N   V35E, T39A, K43N, E44D, K49R, V60I, V118I, K122E, T139R, E169R, K173E, D177E, T200A, E203Q, Q207D, V245T, D250E, A272S, L283I, A288P, I293V, E297A, P313S, V317A, I329V, Q332L, G335D, T338S  
>CU1373-09| codons 1-348
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAELENDGKISRIGPENPYNTPI
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILRPFREQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIQELRDHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLIRGTKPLTEVVPLTAEAE
LELAENREILKESVHGAYYDPSKDLIAEVQKLGQDQWSYQIYQEPFKN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46L, L76V, V82A L10F, L33F, L89V I13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92K  
>CU1373-09| codons 1-99
PQITLWQRPFVTVKIGGQLREALLDTGADDTIFEEIDLPGKWRPKLIGGIGGFIKVRQYD
NIPIEICGHKVIGTVVVGPTPANIIGRNVLTKIGCTLNF

References
Author Title Citation
Kouri, V High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba. J Clin Virol, 2012