Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KI-878 | KI-878 | Japan | 2009 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, I84L, L101I, K156N, I203M |
| >KI-878| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNNELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, M36I, R41K, L63T, I72V |
| >KI-878| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181YC | V179D | E6D, V35I, D123E, I135L, S162C, G196E, T200I, A272P, K277R, E297AITV, E312Q, I326V, P345PT, R358K, K390R, V435L, L452I, R463K, V467VI, H483HQ | L209LV |
| >KI-878| codons 1-560 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIDI CQYMDDLYVGSDLEIEQHRIKIEELRQHVLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTVEAE LELAENREILKQPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQETFKNLKTGKYARMKGA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPILGAETFYVDGAANRETKIGKAGYVTDRGKQKVISLTDTTNQKTELQ AIQLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Chikata, T | Host-specific adaptation of HIV-1 subtype B in the Japanese population. | J Virol, 2014 |