Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KI-895 | KI-895 | Japan | 2009 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, I84M, L101I, K111A, S119T, T125A, I203M, T206S, I208L, I217IV |
| >KI-895| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVATIHTDNGTN FTSTAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDMIASDLQTKELQKQVTKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12A, M36I, L63P, I72T, I93L |
| >KI-895| codons 1-99 PQITLWQRPIVAIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKATGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, D123E, I135V, S162C, K173Q, R211G, A272P, V276I, Q278H, T286A, I293V, I309L, Q334L, M357T, R358K, K366R, K431R, V435M, D460N, R461K, H483Y, A554T |
| >KI-895| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRQQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLGWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKHLCKLLRGAKALTEVVPLTEEAE LELAENRELLKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARTKGA HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEREPIMGAETFYVDGAANRETKLGKAGYVTNKGRQKVVSLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Chikata, T | Host-specific adaptation of HIV-1 subtype B in the Japanese population. | J Virol, 2014 |