<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E10D, V31I, V32I, D41N, L101I, I113V, T124A, T125V, G163E, V201I, T206S, Q216H  
>KI-445| codons 1-288
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPIIAKEIVASCNKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTVHTDNGSN
FTSAVVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIEQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKHITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16A, N37S, Q61N, V77I  
>KI-445| codons 1-99
PQITLWQRPLVTVKIAGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
NILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215D     E36D, K64R, D123E, I135T, I142V, S162C, I178L, V179I, Q207K, V245K, A272P, V276I, I293V, E312A, Q334D, R358K, K374R, K390R, A400T, T403A, K431T, T470P, G490E, K558R  
>KI-445| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVDICTEMEKEGKISKIGPENPYNTPV
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDLII
YQYMDDLYVGSDLEIGQHRTKIEELRKHLLRWGFDTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKAPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARMKGA
HTNDVKQLTEAVQRIATESIVIWGKTPKFRLPIQKETWETWWAEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLPDTTNQKTELQ
AIHLALQDSELEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSAGIRRVL

References
Author Title Citation
Chikata, T Host-specific adaptation of HIV-1 subtype B in the Japanese population. J Virol, 2014