<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D3DE, P30S, I60V, I72V, P90PS, G106A, K188R, V201I, I203M, M275V  
>KI-576| codons 1-288
FLEGIDKAQEEHEKYHSNWRAMASDFNLPSVVAKEIVASCDKCQLKGEAMHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYIEAEVISAETGQETAYFLLKLAARWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRRGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQVAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, N37D, R57K, L63A, A71T, I72T, V77I  
>KI-576| codons 1-99
PQITLWQRPLVTIRVGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVKQYD
QIAIEICGHKTTGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11R, V35I, S68G, K102R, D123E, I135T, S162C, D177E, I178M, I195L, G196E, E204K, Q207E, R211K, E224K, T286V, A288P, E297K, V317A, S322T, T338S, F346Y, M357V, K390R, V435I, T470N, K558R  
>KI-576| codons 1-560
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLELEQHRTKIEKLREHLLKWGFTTPDKKHQKKPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGVKPLTEVIPLTKEAE
LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQGQWSYQIYQEPYKNLKTGKYARVRGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLNDTTNQKTELQ
AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSAGIRRVL

References
Author Title Citation
Chikata, T Host-specific adaptation of HIV-1 subtype B in the Japanese population. J Virol, 2014