<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+NVP+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V K219Q K103N   K20R, E28D, V35T, E36A, T39E, S48T, K82R, V90I, K122E, D123S, I135L, E138A, T139I, S162A, E169K, K173D, T200E, Q207E, R211K, F214L, L228R, V245Q  
>478443| codons 1-255
PISPIETVPVKLKPGMDGPRVKQWPLTDEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNRRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSLNNAIPGIRYQYNVLPQGWKGSPAIFQASMTKILKPFRDQNPDIVI
YQYVDDLYVGSDLEIGQHREKIEELREHLLKWGLTTPDQKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G17D, L19I, K20R, M36I, L63P, H69K, V77I, I93L  
>478443| codons 1-99
PQITLWQRPLVSIKVGDQIREALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Hoffmann, CJ Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa. Antivir Ther, 2013