<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V K70Q Y181C, G190A   V35M, E36A, T39E, K46Q, S48T, K122E, D123N, T139K, K173V, Q174K, T200A, Q207K, R211K, V245Q, D250E  
>452356_2| codons 1-255
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMAICEEMEKEGQITKIGPENPYNTPV
FAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPDIVI
CQYVDDLYVASDLEIGQHRAKIEELRKHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, Q18E, L19I, M36I, R41K, D60E, Q61E, L63S, H69K, L89M, I93L  
>452356_2| codons 1-99
PQITLWQRPLVTIKVGGEIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EISIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hoffmann, CJ Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa. Antivir Ther, 2013